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| Product Name: |
Top Quality Small Molecular API Cediranib (CAS: 28
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| Supply Ability: |
100g |
| Related proudcts |
api, pharmaceutical, intermediate, |
| Specifications |
medicine grade |
| Price Term: |
FOB,CNF,CIF |
| Port of loading: |
Shenzhen |
| Minimum Order |
100 |
| Unit Price: |
2.5 |
|
Top Quality Small Molecular API Cediranib
(CAS: 288383-20-0)
Chemical Information
Product Name Gefitinib hydrochloride
Molecular Formula C22H25Cl2FN4O3
Molecular Weight 483.36
Storage Store at -20°CÂ
Targets VEGFR-1/2/3        PDGFRβ              RETÂ
IC50 22/4/5.2nMÂ Â Â Â Â Â Â Â Â Â Â Â 39nMÂ Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â 35nM
DescriptionÂ
The EGFR is a Mr 170,000 transmembrane glycoprotein with an external binding domain and an intracellular tyrosine kinase domain. Gefitinib (ZD-1839, Iressa) is an Epidermal Growth Factor Receptor-selective Tyrosine Kinase Inhibitor.
DosageÂ
Administration of a 250-mg dose of gefitinib as a dispersion preparation by drink or nasogastric tube achieved a systemic exposure to gefitinib that was consistent with that achieved when gefitinib was administered as a whole tablet. No evidence of tolerability problems associated with the routes of administration studied was observed in these healthy volunteers.Â
COA:
Name: Gefitinib hydrochlorideÂ
CAS No.:
 184475-55-6Â
Content:
>99%Â
Appearance:
A white,Crystalline Powder or colorless crystals
Formula:
C22H25Cl2FN4O3Â Â Â Â
Molecular Weight
483.3633Â
Moisture:
<1mg/mLÂ
Loss on Drying:
�.2%
Residue on ignition:
�.1%
Ethanol:
â‰?1mg/mLÂ
Stability:
at -20°C 2 yearsÂ
Solubility:
DMSO â‰?9mg/mLÂ
Heavy Metals:
�0PPM
Acidity or Alkalinity:
Conform
Chloride:
Conform
Readily Carbonizable Substances:
Conform
Ordinary Impurities:
Conform
FEATURED PRODUCT:
Wuhan Newbio Pharm-tech Co., Ltd.
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1Â 86639-52-3 7-Ethyl-10-Hydroxycamptothecin 25Â 183321-74-6 Erlotinib
2Â 154229-18-2 Abiraterone Acetate 26Â 183319-69-9 Erlotinib Hydrochloride
3Â 50-76-0 Actinomycin D 27Â 159351-69-6 Everolimus
4Â 106941-25-7 Adefovir 28Â 56296-78-7 Fluoxetine Hydrochloride
5Â 850140-72-6 Afatinib 29Â 184475-55-6 Gefitinib Hydrochloride
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| Company: |
Wuhan Newbio Pharm-tech Co., Ltd.
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| Contact: |
Mr. Jason Edwards |
| Address: |
858, East Lake, High-Tech Development Zone, Wuhan, Hubei, China |
| Postcode: |
430075 |
| Tel: |
+86-027-87002705 |
| Fax: |
86-27-87050469 |
| E-mail: |
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