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| Product Name: |
Sitagliptin Phosphate Monohydrate / Sitagliptin Ph
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| Supply Ability: |
100g |
| Related proudcts |
api, pharmaceutical, intermediate, |
| Specifications |
medicine grade |
| Price Term: |
FOB,CNF,CIF |
| Port of loading: |
Shenzhen |
| Minimum Order |
100 |
| Unit Price: |
2.5 |
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Fine Chemicals Sitagliptin Phosphate Hydrate
(CAS: 654671-77-9)
Chemical information
Product Name: Sitagliptin Phosphate Hydrate
Synonym: 7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)Butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazinephosphatemonohydrate;Sitagliptin phosphate monohydrate;Sitagliptin phosphate for research;D06645;Januvia (tn);Sitagliptin phosphate (usan);Sitagliptin phosphate hydrate;Sitagliptin phosphate hydrate (jan)
Appearance: white crystalline
CAS No.: 654671-77-9
Molecular Formula: C16H20F6N5O6P
Molecular Weight: 523.3240802
Purity: 99%+
Packing: Foil Bag or as Required   Â
Product Description:
Sitagliptin phosphate monohydrate is a white to off-white, crystalline, non-hygroscopic powder. It is soluble in water and N,N-dimethyl formamide; slightly soluble in methanol; very slightly soluble in ethanol, acetone, and acetonitrile; and insoluble in isopropanol and isopropyl acetate.
An anti-diabetic (antihyperglycemic) drug of the dipeptidyl peptidase-4 (DPP-4) class. Inhibition of the enzyme DPP-4 is thought to increase Glucagon-like peptide-1 (GLP-1) which inhibits glucagon release , stimulates the insulin release and lowers blood glucose.
What it is used for:
Sitagliptin phosphate monohydrate is used to lower blood sugar levels in patients with type 2 diabetes mellitus alone or in combination with certain other medicines (metformin, medicines such as rosiglitazone and pioglitazone, a sulfonylurea medicine such as glimepiride, gliclazide and glibenclamide), when diet plus exercise or the other medicine(s) do not provide adequate blood sugar level control.
COA:
Tests
Specifications
 Results
Characters
White to off-white crystalline powder
Complies
Identification
IR:similar to Reference Standard
Complies
Appearance of solution
Clear and colorless
Complies
Loss on Drying
�.5%
0.06%
Sulphated Ash
�.2%
0.03%
Heavy metals
�.002%
Complies
Related Compouds
Single Impurity |
| Company: |
Wuhan Newbio Pharm-tech Co., Ltd.
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| Contact: |
Mr. Jason Edwards |
| Address: |
858, East Lake, High-Tech Development Zone, Wuhan, Hubei, China |
| Postcode: |
430075 |
| Tel: |
+86-027-87002705 |
| Fax: |
86-27-87050469 |
| E-mail: |
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