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Wuhan Newbio Pharm-tech Co., Ltd.

Products >> High Purity API Powder Actinomycin D (CAS: 50-76-0

High Purity API Powder Actinomycin D (CAS: 50-76-0

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Description
Product Name: High Purity API Powder Actinomycin D (CAS: 50-76-0
Supply Ability: 100g
Related proudcts api, pharmaceutical, intermediate,
Specifications medicine grade
Price Term: FOB,CNF,CIF
Port of loading: Shenzhen
Minimum Order 100
Unit Price: 2.5

Effective Oncology API Actinomycin D/Dactinomycin 
CAS: 50-76-0

Quick ***ails:
Product Name Dactinomycin
Synonyms 3H-Phenoxazine-1,9-dicarboxamide, 2-amino-N,N'-bis[hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl]-4,6-dimethyl-3-oxo-; hbf 386; Lyovac cosmegen; Meractinomycin; Oncostatin K; X 97; Actactinomycin A IV; Actinomycin 7; Actinomycin AIV; Actinomycindioic D acid, dilactone; Actinomycin C1; actinomycin cl; Actinomycin D; (-)-actinomycin d; actinomycin i; Actinomycin I1; Actinomycin IV; 
MF C62H86N12O16
MW 1255.417

Product Description:
Dactinomycin D  is a metabolite isolated from Streptomyces parvulus that binds to the GpC steps of DNA. The compound acts as an antibiotic and is more effective against gram-positive bacteria than gram negative bacteria. Actinomycin D can induce apoptosis in several cell lines such as lung and prostate cancer lines, and human blood lymphocytes, among others. This compound is also an RNA polymerase inhibitor. In studies it has been observed that Actinomycin D elevates p53 expression, leading to the increase of PUMAα/β (the p53 upregulated modulator of apoptosis protein; PUMA), and can also induce tumornecrosis factor-related apoptosis-inducing ligand (TRAIL)-induced ca***se-dependent and -independent apoptosis.


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Wuhan Newbio Pharm-tech Co., Ltd.
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Company: Wuhan Newbio Pharm-tech Co., Ltd.
Contact: Mr. Jason Edwards
Address: 858, East Lake, High-Tech Development Zone, Wuhan, Hubei, China
Postcode: 430075
Tel: +86-027-87002705
Fax: 86-27-87050469
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